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Gene and DNA Sequence
Record information and status
Record ID
Date of creation
2012-02-06 18:41 UTC (cfia.bchrecords-dossiersccb.acia@canada.ca)
Date of last update
2021-06-22 18:05 UTC (austein.mcloughlin@cbd.int)
Date of publication
2021-06-22 18:05 UTC (austein.mcloughlin@cbd.int)

General information
Name of the gene or DNA sequence
Cold shock protein gene
Alternate Genetic Element Name (synonyms)
Category of DNA sequence
  • Protein coding sequence
Is the gene / DNA sequence is a synthetic molecule?
Donor organism
Donor organism
Bacillus subtilis - Bacillus, BACIU
Characteristics of the protein coding sequence
Name of the protein expressed by the coding sequence
Cold shock protein B (CSPB)
Biological function
CspB is a type of stress-inducible protein that might be able to protect B. subtilis cells from damage caused by ice crystal formation during freezing.
Related trait(s) or use(s) in biotechnology
Additional Information
Additional Information
The gene of the Bacillus subtilis cold shock protein (CspB) encodes an acidic 67-amino-acid protein (pI 4.31) with a predicted molecular mass of 7,365 Da. Northern RNA blot and primer extension studies indicated the presence of one cspB transcript that was initiated 119 bp upstream of the initiation codon and was found to be induced severalfold when exponentially growing B. subtilis cell cultures were transferred from 37 degrees C to 10 degrees C. Consistent with this cold shock induction of cspB mRNA, a six- to eightfold induction of a cspB-directed beta-galactosidase synthesis was observed upon downshift in temperature.

Records referencing this document (119)
119record(s) found
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