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Information Resource
Record information and status
Record ID
103449
Status
Published
Date of creation
2012-05-10 21:20 UTC (dina.abdelhakim@cbd.int)
Date of publication
2012-05-10 21:20 UTC (dina.abdelhakim@cbd.int)

General Information
Title
Dominant lethality and insect population control
Author
Luke Alphey,Morten Andreasen
Author’s contact information
Luke Alphey
luke.alphey@zoo.ox.ac.uk

Department of Zoology, University of Oxford,
South Parks Road, Oxford OX1 3PS, UK
Language(s)
  • English
Publication date
2002-05
Subject
Summary, abstract or table of contents
Abstract:

Recent advances in insect genetic engineering have opened up new possibilities in the genetic control of insect vectors of human diseases. We outline the current state of the sterile insect technique and show how the use of engineered dominant lethals can greatly increase the effectiveness of this approach. We consider alternative strategies based on the use of conditional dominant lethals that are not always active in the environment.
Thematic areas
  • Scientific and technical issues
    • Risk assessment
Background material to the “Guidance on risk assessment of living modified organisms”
Is this document is recommend as background material for the “Guidance on Risk Assessment of Living Modified Organisms”
Yes
Section(s) of the “Guidance on Risk Assessment of Living Modified Organisms” this background material is relevant
  • 5. Risk assessment of living modified mosquitoes species that act as vectors of human and animal diseases
Additional Information
Type of resource
  • Article (journal / magazine / newspaper)
Identifier
doi: 10.1016/S0166-6851(02)00040-3
Publisher and its location
Elsevier
Rights
© 2002, Elsevier
Format
HTML
Source
Molecular and Biochemical Parasitology
Keywords and any other relevant information
Keywords: Dominant lethality; Genetic engineering; Insect population control

Citation: Molecular and Biochemical Parasitology Volume 121, Issue 2, May 2002, Pages 173-178
Access to the resource