| | english | español | français |
Go to record ID

  Home|Finding Information|Record details   Printer-friendly version

Information Resource
Record information and status
Record ID
103496
Status
Published
Date of creation
2012-05-14 12:51 UTC (dina.abdelhakim@cbd.int)
Date of publication
2012-05-14 12:51 UTC (dina.abdelhakim@cbd.int)

General Information
Title
Gene drive systems for insect disease vectors
Author
Steven P. Sinkins and Fred Gould
Author’s contact information
Steven P. Sinkins

Peter Medawar Building & Department of Zoology,
University of Oxford, Oxford
OX1 3PS, UK.

e-mail: steven.sinkins@zoo.ox.ac.uk
Language(s)
  • English
Publication date
2006-06
Subject
Summary, abstract or table of contents
Abstract:

The elegant mechanisms by which naturally occurring selfish genetic elements, such as transposable elements, meiotic drive genes, homing endonuclease genes and Wolbachia, spread at the expense of their hosts provide some of the most fascinating and remarkable subjects in evolutionary genetics. These elements also have enormous untapped potential to be used in the control of some of the world's most devastating diseases. Effective gene drive systems for spreading genes that can block the transmission of insect-borne pathogens are much needed. Here we explore the potential of natural gene drive systems and discuss the artificial constructs that could be envisaged for this purpose.
Thematic areas
  • Scientific and technical issues
    • Risk assessment
Background material to the “Guidance on risk assessment of living modified organisms”
Is this document is recommend as background material for the “Guidance on Risk Assessment of Living Modified Organisms”
Yes
Section(s) of the “Guidance on Risk Assessment of Living Modified Organisms” this background material is relevant
  • 5. Risk assessment of living modified mosquitoes species that act as vectors of human and animal diseases
Additional Information
Type of resource
  • Article (journal / magazine / newspaper)
Identifier
doi:10.1038/nrg1870
Publisher and its location
Nature Publishing Group
Rights
© 2006 Nature Publishing Group
Format
9 page PDF
Source
Nature Reviews: Genetics
Keywords and any other relevant information
Citation: Nature Reviews: Genetics 7: 427-435.