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Information Resource
Record information and status
Record ID
103503
Status
Published
Date of creation
2012-05-14 13:53 UTC (dina.abdelhakim@cbd.int)
Date of publication
2012-05-14 13:53 UTC (dina.abdelhakim@cbd.int)

General Information
Title
Behavioural determinants of gene flow in malaria vector populations: Anopheles gambiae males select large females as mates
Author
FM Okanda, A Dao, BN Njiru, J Arija, HA Akelo, Y Touré, A Odulaja, JC Beier, JI Githure, G Yan, LC Gouagna, BGJ Knols and GF Killeen
Author’s contact information
GF Killeen
Email: Gerry.Killeen@unibas.ch
Language(s)
  • English
Publication date
2002-08-14
Subject
Summary, abstract or table of contents
Abstract

Background: Plasmodium-refractory mosquitoes are being rapidly developed for malaria control but will only succeed if they can successfully compete for mates when released into the wild. Precopulatory behavioural traits maintain genetic population structure in wild mosquito populations and mating barriers have foiled previous attempts to control malaria vectors through sterile male release.

Methods: Varying numbers of virgin male and female Anopheles gambiae Giles, from two strains of different innate sizes, were allowed to mate under standardized conditions in laboratory cages, following which, the insemination status, oviposition success and egg batch size of each female was assessed. The influence of male and female numbers, strain combination and female size were determined using logistic regression, correlation analysis and a simple mechanistic model of male competition for females.

Results: Male An. gambiae select females on the basis of size because of much greater fecundity among large females. Even under conditions where large numbers of males must compete for a smaller number of females, the largest females are more likely to become inseminated, to successfully oviposit and to produce large egg batches.

Conclusions: Sexual selection, on the basis of size, could either promote or limit the spread of malaria-refractory genes into wild populations and needs to be considered in the continued development and eventual release of transgenic vectors. Fundamental studies of behavioural ecology in malaria vectors such as An. gambiae can have important implications for malaria control and should be prioritised for more extensive investigation in the future.
Thematic areas
  • Scientific and technical issues
    • Risk assessment
Background material to the “Guidance on risk assessment of living modified organisms”
Is this document is recommend as background material for the “Guidance on Risk Assessment of Living Modified Organisms”
Yes
Section(s) of the “Guidance on Risk Assessment of Living Modified Organisms” this background material is relevant
  • 5. Risk assessment of living modified mosquitoes species that act as vectors of human and animal diseases
Additional Information
Type of resource
  • Article (journal / magazine / newspaper)
Publisher and its location
BioMed Central (BMC)
Rights
© 2002 Okanda et al
Format
7 page PDF
Source
Malaria Journal
Keywords and any other relevant information
Citation: Malaria Journal 2002, 1:10