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Gene and DNA Sequence
Record information and status
Record ID
103554
Status
Published
Date of creation
2012-05-30 15:14 UTC (german_bch@bvl.bund.de)
Date of last update
2012-07-09 13:55 UTC (dina.abdelhakim@cbd.int)
Date of publication
2012-07-09 13:55 UTC (dina.abdelhakim@cbd.int)

This document is also available in the following languages:
General information
Name of the gene or DNA sequence
c-myc-tag
Abbreviation
TP-c-myc-tag
Category of DNA sequence
  • Transit signal
Is the gene / DNA sequence is a synthetic molecule?
No
Donor organism
Donor organism
Homo sapiens - HUMAN
Additional Information
Additional Information
A c-myc tag is a polypeptide tag derived from the c-myc gene product and is often used in affinity chromatography for protein purification or for immunodetection of corresponding fusion proteins with an anti-myc antibody. The c-myc peptide spans the eleven amino acid sequence EQKLISEEDL and is a relatively small protein-tag, therefore.

c-Myc is a protein that functions as a transcription factor activating the expression of targeted genes upon hetero-dimerisation with an obligate partner. Direct and indirect target genes comprise genes that are involved in cell growth, cell differentiation and apoptosis.

The c-myc oncogene is among the most frequently overexpressed genes in human cancer

Records referencing this document (5)
IDDescription
5record(s) found
Country's Decision or any other Communication1 record
Modified Organism3 records
Risk Assessment1 record