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Information Resource
Record information and status
Record ID
103697
Status
Published
Date of creation
2012-08-02 14:18 UTC (dina.abdelhakim@cbd.int)
Date of publication
2012-08-02 14:18 UTC (dina.abdelhakim@cbd.int)

General Information
Title
Transgene stability and dispersal in forest trees
Author
Mulkh Raj Ahuja
Author’s contact information
60 Shivertown Road
New Paltz, NY
12561

Email: mrahuja@hotmail.com
Language(s)
  • English
Publication date
2009-01-01
Subject
Summary, abstract or table of contents
Abstract:

Transgenics from several forest tree species, carrying a number of commercially important recombinant genes, have been produced, and are undergoing confined field trials in a number of countries. However, there are questions and issues regarding stability of transgene expression and transgene dispersal that need to be addressed in long-lived forest trees. Variation in transgene expression is not uncommon in the primary transformants in plants, and is undesirable as it requires screening a large number of transformants in order to select transgenic lines with acceptable levels of transgene expression. Therefore, the current focus of plant transformation is toward fine tuning of transgene expression and stability in the transgenic forest trees. Although a number of studies have reported a relatively stable transgene expression for several target traits, including herbicide resistance, insect resistance, and lignin modification, there was also some unintended transgene instability in the genetically modified (GM) forest trees. Transgene dispersal from GM trees to feral forest populations and their containment remain important biological and regulatory issues facing commercial release of GM trees. Containment of transgenes must be in place to effectively prevent escape of transgenic pollen, seed, and vegetative propagules in economically important GM forest trees before their commercialization. Therefore, it is important to devise innovative technologies in genetic engineering that lead to genetically stable transgenic trees not only for qualitative traits (herbicide resistance, insect resistance), but also for quantitative traits (accelerated growth, increased height, increased wood density), and also prevent escape of transgenes in the forest trees.
Thematic areas
  • Scientific and technical issues
    • Risk assessment
Background material to the “Guidance on risk assessment of living modified organisms”
Is this document is recommend as background material for the “Guidance on Risk Assessment of Living Modified Organisms”
Yes
Section(s) of the “Guidance on Risk Assessment of Living Modified Organisms” this background material is relevant
Additional Information
Type of resource
  • Report / Review / Fact sheet / Notes
Identifier
DOI: 10.1007/s00468-009-0362-8
Publisher and its location
Springer
Rights
Copyright © 2009, Springer-Verlag
Format
HTML
Source
Trees- Structure and Function
Keywords and any other relevant information
Keywords  Forest trees - Recombinant genes - Transgenic trees - Transgene stability - Gene flow - Transgene dispersal - Containment
Access to the resource