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Gene and DNA Sequence
Record information and status
Record ID
103933
Status
Published
Date of creation
2012-09-24 15:55 UTC (dina.abdelhakim@cbd.int)
Date of last update
2013-09-24 19:55 UTC (dina.abdelhakim@cbd.int)
Date of publication
2013-09-24 19:55 UTC (dina.abdelhakim@cbd.int)

General information
Name of the gene or DNA sequence
Acetohydroxy acid synthase gene terminator
Alternate Genetic Element Name (synonyms)
Acetolactate Synthase (ALS) gene terminator
Abbreviation
T-AHAS
Category of DNA sequence
  • Terminator
Is the gene / DNA sequence is a synthetic molecule?
No
Donor organism
Donor organism
Arabidopsis thaliana - Thale cress, Mouse-ear cress, Arabidopsis, ARATH
Additional Information
Additional Information
AHAS is an essential enzyme for many organisms as it catalyzes the first step in the biosynthesis of the branched-chain amino acids valine, isoleucine, and leucine.

A common mutant form of the ahas gene was isolated from a herbicide-resistant Arabidopsis thaliana which differs from the wild type gene by only a single base pair. A "G" to "A" point mutation results in a single amino acid substitution in which the serine residue at position 653 is replaced by asparagine (S653N)

Tests using the mutant isoform of the ahas gene showed that it confers tolerance to sulfonylurea herbicides in plants. The ahas mutant isoform may, therefore, be used as a selectable marker in transgenic plants.

Records referencing this document (7)
IDDescription
7record(s) found
Country's Decision or any other Communication3 records
Modified Organism2 records
Risk Assessment2 records