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Gene and DNA Sequence
Record information and status
Record ID
104939
Status
Published
Date of creation
2013-06-24 08:36 UTC (german_bch@bvl.bund.de)
Date of last update
2014-08-08 17:47 UTC (dina.abdelhakim@cbd.int)
Date of publication
2014-08-08 17:47 UTC (dina.abdelhakim@cbd.int)

This document is also available in the following languages:
General information
Name of the gene or DNA sequence
ArsR gene
Abbreviation
CS-arsR-ECOLX
Category of DNA sequence
  • Protein coding sequence
Is the gene / DNA sequence is a synthetic molecule?
No
Donor organism
Donor organism
Escherichia coli - ECOLX
Characteristics of the protein coding sequence
Name of the protein expressed by the coding sequence
ArsR Transcriptional Repressor
Biological function
The gene arsR stems from the E. coli-specific plasmid R773 and encodes for a transcriptional regulator with binding sites for arsenic compounds.

It is a repressor protein that binds to its promoter in the absence of arsenic compounds therefore repressing the expression of downstream genes.

Arsenic compounds that are taken up by bacterial cells form a complex with ArsR, thereby allosterically preventing the association of ArsR with the promoter. Thus, the transcription of downstream genes is induced.
Related trait(s) or use(s) in biotechnology
  • Tolerance to abiotic stress

Records referencing this document (2)
IDDescription
2record(s) found
Modified Organism1 record
Risk Assessment1 record