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Biosafety Virtual Library Resources
(VLR)
published: 16 Jun 2013
last updated: 01 Aug 2013
A long-term toxicology study on pigs fed a combined genetically modified (GM) soy and GM maize diet
EN
Journal of Organic Systems. Australia
EN
2013-06
EN
original document
EN
Copyright held by authors. Article is open source.
EN
- Language of resource [ English ]
A significant number of genetically modified (GM) crops have been approved to enter
human food and animal feed since 1996, including crops containing several GM genes
'stacked' into the one plant. We randomised and fed isowean pigs (N=168) either a mixed
GM soy and GM corn (maize) diet (N=84) or an equivalent non-GM diet (N=84) in a longterm
toxicology study of 22.7 weeks (the normal lifespan of a commercial pig from
weaning to slaughter). Equal numbers of male and female pigs were present in each
group. The GM corn contained double and triple-stacked varieties. Feed intake, weight
gain, mortality and blood biochemistry were measured. Organ weights and pathology
were determined post-mortem. There were no differences between pigs fed the GM and
non-GM diets for feed intake, weight gain, mortality, and routine blood biochemistry
measurements. The GM diet was associated with gastric and uterine differences in pigs.
GM-fed pigs had uteri that were 25% heavier than non-GM fed pigs (p=0.025). GM-fed
pigs had a higher rate of severe stomach inflammation with a rate of 32% of GM-fed pigs
compared to 12% of non-GM-fed pigs (p=0.004). The severe stomach inflammation was
worse in GM-fed males compared to non-GM fed males by a factor of 4.0 (p=0.041), and
GM-fed females compared to non-GM fed females by a factor of 2.2 (p=0.034).
EN
human food and animal feed since 1996, including crops containing several GM genes
'stacked' into the one plant. We randomised and fed isowean pigs (N=168) either a mixed
GM soy and GM corn (maize) diet (N=84) or an equivalent non-GM diet (N=84) in a longterm
toxicology study of 22.7 weeks (the normal lifespan of a commercial pig from
weaning to slaughter). Equal numbers of male and female pigs were present in each
group. The GM corn contained double and triple-stacked varieties. Feed intake, weight
gain, mortality and blood biochemistry were measured. Organ weights and pathology
were determined post-mortem. There were no differences between pigs fed the GM and
non-GM diets for feed intake, weight gain, mortality, and routine blood biochemistry
measurements. The GM diet was associated with gastric and uterine differences in pigs.
GM-fed pigs had uteri that were 25% heavier than non-GM fed pigs (p=0.025). GM-fed
pigs had a higher rate of severe stomach inflammation with a rate of 32% of GM-fed pigs
compared to 12% of non-GM-fed pigs (p=0.004). The severe stomach inflammation was
worse in GM-fed males compared to non-GM fed males by a factor of 4.0 (p=0.041), and
GM-fed females compared to non-GM fed females by a factor of 2.2 (p=0.034).
Yes
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BCH-LMO-SCBD-14809-8 Living Modified Organism MON-ØØ863-5 × MON-ØØ81Ø-6 × MON-ØØ6Ø3-6 - Roundup Ready™ YieldGard™ maizeMonsanto | Resistance to antibiotics (Kanamycin), Resistance to diseases and pests (Insects, Coleoptera (beetles), Lepidoptera (butterflies and moths), European corn borer (Ostrinia nubilalis)), Resistance to herbicides (Glyphosate)
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BCH-LMO-SCBD-14885-8 Living Modified Organism MON-ØØ6Ø3-6 × MON-ØØ81Ø-6 - Roundup Ready™ YieldGard™ maizeMonsanto | Resistance to diseases and pests (Insects, Lepidoptera (butterflies and moths), European corn borer (Ostrinia nubilalis)), Resistance to herbicides (Glyphosate)
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BCH-LMO-SCBD-14776-17 Living Modified Organism MON-ØØ6Ø3-6 - Roundup Ready™ maizeMonsanto | Resistance to herbicides (Glyphosate)
Yes
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BCH-ORGA-SCBD-246-6 Organism Zea mays (Maize, Corn, MAIZE)Crops
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BCH-ORGA-SCBD-10453-6 Organism Glycine max (Soybean, Soya bean, Soya, SOYBN)Crops
No
Identifier (ISBN, ISSN, etc.)
ISSN 1177-4258
Format
17 pages. Requires pdf reader for viewing.
Keywords and any other relevant information
GMO, GM corn, GM soy, GM animal feed, toxicology, stomach inflammation,
uterus weight
How to obtain the resource
http://www.organic-systems.org/journal/81/8106.pdf
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