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Modified Organism
MOUSTICIDE™
Record information and status
Record ID
106444
Status
Published
Date of creation
2015-02-27 07:49 UTC (al@entogenex.com)
Date of publication
2015-02-27 19:11 UTC (dina.abdelhakim@cbd.int)

Living Modified Organism identity
The image below identifies the LMO through its unique identifier, trade name and a link to this page of the BCH. Click on it to download a larger image on your computer. For help on how to use it go to the LMO quick-links page.

LMO name
MOUSTICIDE™
Transformation event
TMOF_yeast
Developer(s)
Mr Mohd Alhafis Rusdi
Technology Officer
Regulatory
EntoGenex Industries Sdn. Bhd.
D-3A-08, Plaza Mont' Kiara
No. 2 Jalan Kiara, Mont' Kiara
50480 Kuala Lumpur
Malaysia
Kuala Lumpur
Malaysia, 50480
Phone:+603 6203 5531 / 6203 5532
Fax:+603 6206 5533
Email:al@entogenex.com
Url:http://entogenex.com/
Description
MOUSTICIDE™ is a biolarvicide that is, amongst other things, composed of heat inactivated Pichia pastoris KM71H strain transformed with pPICZ B plasmid containing gene sequences for expression of the Trypsin Modulating Oostatic Factor (TMOF) peptide.

Exposure of mosquito larvae to the TMOF peptide results in suppression of  larval growth and development.
Recipient Organism or Parental Organisms
The term Recipient organism refers to an organism (either already modified or non-modified) that was subjected to genetic modification, whereas Parental organisms refers to those that were involved in cross breeding or cell fusion.
Pichia pastoris - Yeast, PICPA
Characteristics of the transformation process
Vector
pPICZ B
Techniques used for the modification
  • Electroporation
Genetic elements construct
 
Alcohol oxidase 1 gene promoter
0.00 Kb
 
 
Trypsin Modulating Oostatic Factor gene
0.00 Kb
 
 
Alcohol oxidase 1 gene terminator
0.00 Kb
 
Further details
Notes regarding the genetic elements introduced or modified in this LMO
The gene responsible for the modified trait(s) is a synthetic DNA sequence optimized for codon usage by Pichia pastoris to express the TMOF decapeptide as isolated from Aedes aegypti mosquito.
LMO characteristics
Modified traits
Common use(s)
  • Biolarvicide

Records referencing this document (4)
IDDescription
4record(s) found
Country's Decision or any other Communication2 records
Risk Assessment2 records