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Gene and DNA Sequence
Record information and status
Record ID
107873
Status
Published
Date of creation
2015-03-24 07:46 UTC (german_bch@bvl.bund.de)
Date of publication
2015-04-13 17:47 UTC (dina.abdelhakim@cbd.int)

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General information
Name of the gene or DNA sequence
CoA-transferase beta subunit gene
Abbreviation
CS-ipdB-RHOE1
Category of DNA sequence
  • Protein coding sequence
Is the gene / DNA sequence is a synthetic molecule?
No
Donor organism
Donor organism
Rhodococcus equi - RHOE1
Characteristics of the protein coding sequence
Name of the protein expressed by the coding sequence
IpdB - CoA-transferase beta subunit
Biological function
The gene ipdB (REQ_07160) is an ortholog of rv3552 of Mycobacterium tuberculosis and likewise localized in the cholesterol catabolic gene cluster of its bacterial chromosome of Rhodococcus equi. The encoded protein IpdB (GenBank accession CBH46833) carries a COG2057 signature of AtoA, the beta subunit acetoacetyl-CoA transferase of E. coli. It is thought that IpdB is an beta subunit of a heterodimeric coenzyme A transferase involved in steroid catabolism, more specific in methylhexahydroindanone propionate degradation. It was shown that the cholesterol catabolism is important for pathogenicity of R. equi.
Related trait(s) or use(s) in biotechnology

Records referencing this document (3)
IDDescription
3record(s) found
Country's Decision or any other Communication1 record
Modified Organism1 record
Risk Assessment1 record