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Modified Organism
Domestic goat modified to produce human lactoferrin
Record information and status
Record ID
108045
Status
Published
Date of creation
2015-05-15 12:59 UTC (g.mozgova@yandex.ru)
Date of publication
2015-05-26 18:13 UTC (dina.abdelhakim@cbd.int)

Living Modified Organism identity
The image below identifies the LMO through its unique identifier, trade name and a link to this page of the BCH. Click on it to download a larger image on your computer. For help on how to use it go to the LMO quick-links page.

LMO name
Domestic goat modified to produce human lactoferrin
Transformation event
rhLF Goat
Developer(s)
Dr Alexander Ivanovich Budevich
head of laboratory
Laboratory of reproduction, embryo transfer and animal transgenesis
Republican Unitary Enterprise "Scientific and Practical Center of the National Academy of Sciences of Belarus on Animal Husbandry"
Frunze,11
Zhodino, Minsk district
Belarus, 222167
Phone:+375177522184
Fax:+375177535283
Email:belniig@tut.by
Url:http://belniig.by/
Description
A human lactoferrin coding sequence was incorporated into the goat genome resulting in the synthesis of the biologically active glycoprotein, rhLF, in the mammary gland of the transgenic goats.
Recipient Organism or Parental Organisms
The term Recipient organism refers to an organism (either already modified or non-modified) that was subjected to genetic modification, whereas Parental organisms refers to those that were involved in cross breeding or cell fusion.
Capra aegagrus hircus - Domestic goat, Goat, CAPHI
Characteristics of the transformation process
Vector
hLf3, hLf5
Techniques used for the modification
  • Microinjection
Introduced or modified genetic elements
Some of these genetic elements may be present as fragments or truncated forms. Please see notes below, where applicable.
Recombinant human lactoferrin coding sequence - Homo sapiens - HUMAN
Production of medical or pharmaceutical compounds (human or animal)
Beta-casein gene promoter - Capra aegagrus hircus - Domestic goat, Goat, CAPHI
LMO characteristics
Modified traits
  • Production of medical or pharmaceutical compounds (human or animal)
Common use(s)
  • Research