Record details

Living Modified Organism identity

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LMO name

Insect resistant herbicide tolerant cotton

Transformation event

GHB614 x GHB119 x COT102

Unique identifier

BCS-GHØØ2-5 x BCS-GHØØ5-8 x SYN-IR1Ø2-7

Developer(s)

Record #7088

Bayer CropScience

Url:	Bayer CropScience Homepage

Record #101875

Syngenta Seeds GmbH

Syngenta Seeds GmbH
Zum Knipkenbach 20

Bad Salzuflen

Germany, 32107

Phone:	+49 52 22 5308-0
Fax:	+49 52 22 5308-12
Email:	info.seeds@syngenta.com
Url:	Syngenta Seeds Germany

Description

BCS-GHØØ2-5 x BCS-GHØØ5-8 x SYN-IR1Ø2-7 cotton is the product of the conventional breeding of each of the parental organisms to produce cotton that expresses each of Vip3a, Cry2Ae, PAT, EPSPS, and hpt. The expression of these genes are expected to confer resistance to Lepidoptera and tolerance to glufosinate herbicide and glyphosate herbicide as well as resistance to the antibiotic hygromycin B.

Recipient Organism or Parental Organisms

The term Recipient organism refers to an organism (either already modified or non-modified) that was subjected to genetic modification, whereas Parental organisms refers to those that were involved in cross breeding or cell fusion.

Record #12080

Gossypium hirsutum - Cotton

Record #46334

BCS-GHØØ2-5 - GlyTol™ Cotton GHB614

Bayer CropScience Resistance to herbicides - Glyphosate

Show detection method(s)

Record #14992

SYN-IR1Ø2-7 - VIPCOT™ Cotton

Resistance to antibiotics - Hygromycin Resistance to diseases and pests - Insects - Lepidoptera (butterflies and moths) Selectable marker genes and reporter genes

Show detection method(s)

Record #101898

BCS-GHØØ5-8 - Herbicide-tolerant and lepidoptera-resistant cotton

Bayer BioScience N.V. Resistance to diseases and pests - Insects - Lepidoptera (butterflies and moths) - Cotton bollworm (Helicoverpa spp.), armyworm (Spodoptera frugiperda) Resistance to herbicides - Glufosinate

Show detection method(s)

Characteristics of the transformation process

Vector

pTEM2, pCOT-1 and pTEM12

Techniques used for the modification

Cross breeding

Genetic elements construct

Ubiquitin gene 3 promoter

#101874

0.00 Kb

Hygromycin B phosphotransferase gene

#14991

0.00 Kb

Nopaline Synthase Gene Terminator

#100269

0.00 Kb

Actin 2 Gene Promoter

#104517

0.00 Kb

Vegetative insecticidal protein 3A

#14990

0.00 Kb

Nopaline Synthase Gene Terminator

#100269

0.00 Kb

CaMV 35S promoter

#100287

0.48 Kb

5' untranslated leader of chlorophyll a/b-binding protein

#101901

0.07 Kb

rbcS Transit Peptide

#101902

0.16 Kb

Cry2Ae

#101895

1.90 Kb

CaMV 35S terminator

#100290

0.27 Kb

Nopaline Synthase Gene Terminator

#100269

0.31 Kb

Phosphinothricin N-acetyltransferase gene

#14972

0.55 Kb

CsVMV promoter

#101900

0.54 Kb

Histone H4 gene Promoter

#104647

1.01 Kb

Histone H3 Gene II intron 1

#104648

0.52 Kb

Optimized Transit Peptide

#101419

0.37 Kb

Double Mutant 5-enolpyruvylshikimate-3-phosphate synthase

#46333

1.34 Kb

Histone H4 gene 3' UTR

#104646

0.74 Kb

Further details

Notes regarding the genetic elements introduced or modified in this LMO

DNA insert from COT102 vector pCOT-1:
Cotton tolerant to lepidopteran pests through introduction of the vip3A(a) gene which codes for an insecticidal protein that targets lepidopteran insect species. The aph4 gene, coding for hygromycin-B phosphotransferase (APH4) was used as a selectable marker.

DNA insert from GHB614 vector pTEM2
Contains a single copy of the 2mepsps gene and regulatory elements which confers tolerance to the herbicide glyphosate

DNA insert from GHB119 vector pTEM12
Contains one full copy of the Cry2Ae gene which expressed an insecticidal crystal protein that protects against lepidopteran pests and the bar gene which confers tolerance to the herbicide glufosinate.

For additional information on this LMO, please refer to the records of the parental LMOs.

LMO characteristics

Modified traits

Resistance to diseases and pests
- Insects
  - Lepidoptera (butterflies and moths)
Resistance to herbicides
- Glufosinate
- Glyphosate
Selectable marker genes and reporter genes

Common use(s)

Food
Feed
Fiber / Textile