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Modified Organism
MON-87419-8 - Dicamba and Glufosinate Tolerant Maize
Record information and status
Record ID
Date of creation
2017-01-20 19:36 UTC (dina.abdelhakim@cbd.int)
Date of last update
2019-04-24 13:56 UTC (austein.mcloughlin@cbd.int)
Date of publication
2019-04-24 13:56 UTC (austein.mcloughlin@cbd.int)

Living Modified Organism identity
The image below identifies the LMO through its unique identifier, trade name and a link to this page of the BCH. Click on it to download a larger image on your computer. For help on how to use it go to the LMO quick-links page.

LMO name
Dicamba and Glufosinate Tolerant Maize
Transformation event
Unique identifier
800 North Lindbergh Blvd.
St. Louis, MO
United States of America, 63167
Phone:+ 1 314 694-1000
Fax:+1 314 694-3080
Maize modified with the insertion of transformation cassette containing the Dicamba monooxygenase (DMO) gene and Phosphinothricin N-acetyltransferase (PAT) gene to confer resistance to the herbicides Dicamba and Glufosinate respectively.
Recipient Organism or Parental Organisms
The term Recipient organism refers to an organism (either already modified or non-modified) that was subjected to genetic modification, whereas Parental organisms refers to those that were involved in cross breeding or cell fusion.
Zea mays - Maize, Corn, MAIZE
Characteristics of the transformation process
Techniques used for the modification
  • Agrobacterium-mediated DNA transfer
Genetic elements construct
Ubiquitin gene promoter
1.64 Kb
Ubiquitin leader sequence
0.10 Kb
Ubiquitin Intron Sequence
1.04 Kb
Phosphinothricin N-acetyltransferase gene
0.55 Kb
RA5B gene terminator
0.21 Kb
PC1SV Promoter
0.43 Kb
5' untranslated leader from chlorophyll a/b-binding protein
0.06 Kb
Rice actin 1, intron
0.48 Kb
Chloroplast Transit Peptide 4
0.22 Kb
Dicamba monooxygenase gene
1.02 Kb
Heat shock protein 17.3 terminator
0.21 Kb
Further details
Notes regarding the genetic elements introduced or modified in this LMO
The Streptomyces viridochromogenes phosphinothricin N-acetyltransferase (PAT) gene is under the control of the Andropogon gerardii ubiquitin (Ubq) gene promoter and the Oryza sativa alpha-amylase/trypsin inhibitor terminator. The transcript includes the A. gerardii 5' untranslated leader sequence and an intron from Ubq before the PAT.

The Stenotrophomonas maltophilia Dicamba monooxygenase (DMO) gene is under control of the peanut chlorotic streak caulimovirus (PC1SV) Full-length transcipt (FLt) promoter and the Triticum aestivum (wheat) heat shock protein 17 terminator. The transcript produced contains the wheat chlorophyll a/b-binding 5' untranslated leader sequence (for improved gene expression), the Oryza sativa Actin 1 untranslated region (UTR) and intron (for improved gene expression), the targeting and UTR of Petunia hybrida Chloroplast Transit Peptide 4, and DMO.

- Originally, the plasmid vector contained two T-DNA elements that were inserted during the initial transformation event: one containing the dmo and pat expression cassettes, and a second containing a cp4 epsps expression cassette. The cp4 epsps expression cassette is regulated by the Ract1 promoter from Oryza sativa, the Ract1 5′ untranslated leader from Oryza sativa, the Ract1 intron from Oryza sativa, the CTP2 targeting sequence from Arabidopsis thaliana, and the nos 3′ untranslated region from Agrobacterium tumefaciens. Subsequent traditional breeding, segregation, selection, and screening were used to isolate those plants that contain the dmo and pat expression cassettes (T-DNA I) and do not contain the cp4 epsps expression cassette (T-DNA II).
- Molecular characterization of MON 87419 indicated that a single copy of T-DNA I was integrated into the maize genome at a single intact locus that includes all expected elements within the insert, with the exception of incomplete Right and Left Border sequences. These analyses also showed no PV-ZMHT507801 backbone elements or T-DNA II sequences were present in the event.

LMO characteristics
Modified traits
Common use(s)
  • Food
  • Feed
Additional Information
Other relevant website address or attached documents

Records referencing this document (16)
16record(s) found
Country's Decision or any other Communication5 records
Modified Organism5 records
Risk Assessment6 records