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Modified Organism
Potato modified for increased tuber weight
Record information and status
Record ID
Date of creation
2017-02-07 08:11 UTC (german_bch@bvl.bund.de)
Date of publication
2017-02-10 22:34 UTC (dina.abdelhakim@cbd.int)

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Living Modified Organism identity
The image below identifies the LMO through its unique identifier, trade name and a link to this page of the BCH. Click on it to download a larger image on your computer. For help on how to use it go to the LMO quick-links page.

LMO name
Potato modified for increased tuber weight
Transformation event
B33-alphaUMPS 5, B33-alphaUMPS 8, B33-alphaUMPS 73, B33-alphaUMPS 76
Max Planck Institute of Molecular Plant Physiology (MPIMP)
Max-Planck-Institut für Molekulare Pflanzenphysiologie
Am Mühlenberg 1
Germany, 14476
Phone:+49 331 567 - 80
Fax:+49 331 567 - 84 08
Url:Max-Planck-Institut für Molekulare Pflanzenphysiologie
The genetically modified potatoes were transformed to  constitutively express the cDNA coding of uridine monophosphate synthase (UMPS) from Solanum tuberosum in an antisense orientation. This results in the downregulation of endogenous UMPS which is expected to lead to a reduction in the de novo synthesis of uridine monophosphate (UMP).

The resulting altered UMP ratio indirectly influences starch biosynthesis. In wild-type plants, a portion of the cellular  glucose-1-phosphate is not used for starch biosynthesis but is converted to sucrose with the help of UDP-glucose-pyrophosphorylase (UGPase) and sucrose synthase. UGPase needs UTP for the synthesis of UDP-glucose. The reduced de novo synthesis of UMP would, by extension, lead to a reduced UTP content and therfore prevent the reconversion of glucose-1-phosphate to sucrose. More glucose-1-phosphate will, therefore, be available for starch biosynthesis, resulting in a 10-20% increase in tuber weight maintaining a constant density.
Recipient Organism or Parental Organisms
The term Recipient organism refers to an organism (either already modified or non-modified) that was subjected to genetic modification, whereas Parental organisms refers to those that were involved in cross breeding or cell fusion.
Solanum tuberosum - Potato, SOLTU
Related LMOs
Potato modified for increased tuber weight
Changes in physiology and/or production - Yield Resistance to antibiotics - Kanamycin
Characteristics of the transformation process
Derivative of pBIN19
Techniques used for the modification
  • Agrobacterium-mediated DNA transfer
Genetic elements construct
B33 gene promotor
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Uridine monophosphate synthase gene
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Octopine Synthase Gene Terminator
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Nopaline Synthase Gene Promoter
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Neomycin Phosphotransferase II
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Nopaline Synthase Gene Terminator
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Further details
LMO characteristics
Modified traits
Common use(s)
  • Research

Records referencing this document (3)
3record(s) found
Country's Decision or any other Communication1 record
Modified Organism1 record
Risk Assessment1 record