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Gene and DNA Sequence
Record information and status
Record ID
Date of creation
2017-03-21 15:44 UTC (german_bch@bvl.bund.de)
Date of last update
2017-05-18 15:02 UTC (dina.abdelhakim@cbd.int)
Date of publication
2017-05-18 15:02 UTC (dina.abdelhakim@cbd.int)

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General information
Name of the gene or DNA sequence
Imidazoleglycerol-phosphate dehydratase gene
Category of DNA sequence
  • Protein coding sequence
Is the gene / DNA sequence is a synthetic molecule?
Donor organism
Donor organism
Saccharomyces cerevisiae - Yeast, YEASX
Characteristics of the protein coding sequence
Name of the protein expressed by the coding sequence
imidazoleglycerin-phosphate-dehydratase (IGPD)
Biological function
The enzyme imidazoleglycerol-phosphate dehydratase (IGPD) catalyses the conversion of imidazoleglycerol-phosphate to imidazoleacetol-phosphate which is a critical step in the histidine biosynthesis pathway.

It is used in research as a bacterial selection marker, whereby mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts.
Related trait(s) or use(s) in biotechnology
  • Selectable marker genes and reporter genes

Records referencing this document (3)
3record(s) found
Country's Decision or any other Communication1 record
Modified Organism1 record
Risk Assessment1 record