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Gene and DNA Sequence
Record information and status
Record ID
Date of creation
2017-03-22 10:57 UTC (german_bch@bvl.bund.de)
Date of last update
2017-05-16 16:14 UTC (dina.abdelhakim@cbd.int)
Date of publication
2017-05-16 16:14 UTC (dina.abdelhakim@cbd.int)

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General information
Name of the gene or DNA sequence
Lac operon promoter
Category of DNA sequence
  • Promoter
Is the gene / DNA sequence is a synthetic molecule?
Donor organism
Donor organism
Escherichia coli - ECOLX
Additional Information
Additional Information
The Lac promoter initiates transcription of the genes of the Lac operon.

It is regulated by the actions of the Lac repressor binding to the Lac operator in the absence of lactose therefore preventing RNA polymerase from binding to Lac promoter.

The repressor is inactivated in the presence of lactose, which binds to the repressor. This causes a confomational change that prevents it from binding to the operator region therefore enabling the transcription machinery to bind to the promoter leading to the expression of the three Lac genes of the operon.
Other relevant website address or attached documents

Records referencing this document (3)
3record(s) found
Country's Decision or any other Communication1 record
Modified Organism1 record
Risk Assessment1 record