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Gene and DNA Sequence
Record information and status
Record ID
111880
Status
Published
Date of creation
2017-03-21 15:36 UTC (german_bch@bvl.bund.de)
Date of last update
2017-05-16 15:05 UTC (dina.abdelhakim@cbd.int)
Date of publication
2017-05-16 15:06 UTC (dina.abdelhakim@cbd.int)

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General information
Name of the gene or DNA sequence
Lac operon repressor gene
Abbreviation
CS-lacI-ECOLX
Category of DNA sequence
  • Protein coding sequence
Is the gene / DNA sequence is a synthetic molecule?
No
Donor organism
Donor organism
Escherichia coli - ECOLX
Characteristics of the protein coding sequence
Name of the protein expressed by the coding sequence
Lactose operon repressor
Biological function
The lactose operon repressor is a DNA binding protein that functions to regulate the expression of the Lac operon.

In the absence of lactose it inhibits the expression of the genes lacZ-lacY-lacA which code for the lactose-degrading enzymes of the operon by binding to the operator region of the Lac operon, thus hindering RNA polymerase from binding to the Lac promoter.

The repressor is inactivated by lactose which binds to the repressor. This causes a confomational change that prevents it from binding to the operator region.
Additional Information
Other relevant website address or attached documents

Records referencing this document (3)
IDDescription
3record(s) found
Country's Decision or any other Communication1 record
Modified Organism1 record
Risk Assessment1 record