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Genetic element
(GENE)
last updated: 22 Mar 2017
Lac operator region
EN
BS-lac-ECOLX
EN
Other (Binding site)
No
-
BCH-ORGA-SCBD-14930-5 Organism Escherichia coli (ECOLX)Bacteria
EN
The Lac operator is a protein binding site for the lac operon repressor which work to regulate the expression of the Lac operon.
In the absence of lactose the repressor binds to the operator region which leads to the inhibition of the expression of the genes lacZ-lacY-lacA, which code for the lactose-degrading enzymes of the operon by hindering RNA polymerase from binding to the Lac promoter.
The repressor is inactivated in the presence of lactose which binds to the repressor. This causes a confomational change that prevents it from binding to the operator region.
EN
In the absence of lactose the repressor binds to the operator region which leads to the inhibition of the expression of the genes lacZ-lacY-lacA, which code for the lactose-degrading enzymes of the operon by hindering RNA polymerase from binding to the Lac promoter.
The repressor is inactivated in the presence of lactose which binds to the repressor. This causes a confomational change that prevents it from binding to the operator region.
- Lac Operon - Wikipedia [ English ]
- Lac Operon - Wikipedia [ German ]
