| | english | español | français |
Go to record ID

  Home|Finding Information|Record details   Printer-friendly version

Gene and DNA Sequence
Record information and status
Record ID
111905
Status
Published
Date of creation
2017-03-22 10:56 UTC (german_bch@bvl.bund.de)
Date of publication
2017-05-16 15:30 UTC (dina.abdelhakim@cbd.int)

This document is also available in the following languages:
General information
Name of the gene or DNA sequence
Lac operator region
Abbreviation
BS-lac-ECOLX
Category of DNA sequence
  • Binding site
Is the gene / DNA sequence is a synthetic molecule?
No
Donor organism
Donor organism
Escherichia coli - ECOLX
Additional Information
Additional Information
The Lac operator is a protein binding site for the lac operon repressor which work to regulate the expression of the Lac operon.

In the absence of lactose the repressor binds to the operator region which leads to the inhibition of the expression of the genes lacZ-lacY-lacA, which code for the lactose-degrading enzymes of the operon by hindering RNA polymerase from binding to the Lac promoter.

The repressor is inactivated in the presence of lactose which binds to the repressor. This causes a confomational change that prevents it from binding to the operator region.
Other relevant website address or attached documents