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Modified Organism
GM Leishmania major [DRAFT]
Record information and status
Record ID
113944
Status
Published
Date of creation
2018-05-21 08:45 UTC (hana.jirakova@mzp.cz)
Date of publication
2018-10-31 14:43 UTC (melissa.willey@cbd.int)

Living Modified Organism identity
The image below identifies the LMO through its unique identifier, trade name and a link to this page of the BCH. Click on it to download a larger image on your computer. For help on how to use it go to the LMO quick-links page.

Transformation event
GM Leishmania major [DRAFT]
Developer(s)
Palacky University Olomouc
Institute of Molecular and Translational Medicine
Palacky University Olomouc
Olomouc
Czech Republic, 77900
Phone:+420 585 632 111
Email:reception@imtm.upol.cz
Url:The Institute of Molecular and Translational Medicine, University Palacky
Description
Trangenic Leishmania major expressing reporter  fluorescent protein and resistant to streptothricin antibiotic.
Vector carrying gene for DsRed reporter protein and pLEXSY-red-sat2 gene for resistance to Nourseothricin (streptothricin) have been used for its development. GM Leishmania is used in the study to identify new medicine compounds active against Leishmania.
Recipient Organism or Parental Organisms
The term Recipient organism refers to an organism (either already modified or non-modified) that was subjected to genetic modification, whereas Parental organisms refers to those that were involved in cross breeding or cell fusion.
Leishmania major [DRAFT]
Characteristics of the transformation process
Vector
Vector carrying gene for DsRed reporter protein and pLEXSY-red-sat2 gene for resistance to Nourseothricin (streptothricin)
Techniques used for the modification
  • Electroporation
  • Transfection
Introduced or modified genetic elements
Some of these genetic elements may be present as fragments or truncated forms. Please see notes below, where applicable.
DsRed reporter protein [DRAFT]
Selectable marker genes and reporter genes
LMO characteristics
Modified traits
  • Selectable marker genes and reporter genes
Common use(s)
  • Research