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Gene and DNA Sequence
Record information and status
Record ID
114712
Status
Published
Date of creation
2019-05-21 15:59 UTC (austein.mcloughlin@cbd.int)
Date of last update
2019-05-21 16:11 UTC (austein.mcloughlin@cbd.int)
Date of publication
2019-05-21 16:11 UTC (austein.mcloughlin@cbd.int)

General information
Name of the gene or DNA sequence
Anchored core protein C
Alternate Genetic Element Name (synonyms)
Capsid protein C
Abbreviation
ancC
Category of DNA sequence
  • Protein coding sequence
Is the gene / DNA sequence is a synthetic molecule?
No
Donor organism
Donor organism
Yellow fever virus - YFV 17D
Donor organism point of collection
Yellow fever virus strain 17 D (vaccine strain)
Characteristics of the protein coding sequence
Biological function
Anchored protein C (ancC) binds the host cell membrane and gathers the viral RNA genome to form the core of the mature viral particles. During viral entry into the host cell, the protein may induce genome penetration into host cytoplasm. Furthermore, ancC can migrate to the nucleus to modulate host functions.
AncC (nucleotide position 119..481) also contains protein C (nucleotide position 119..421), which is produced upon further processing by the host cell and interferes with host Dicer to prevent RNA interference.

Records referencing this document (3)
IDDescription
3record(s) found
Country's Decision or any other Communication1 record
Modified Organism1 record
Risk Assessment1 record