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Genetic element
(GENE)
last updated: 21 May 2019
Nonstructural protein 1
EN
NS1
EN
Protein coding sequence
No
-
BCH-ORGA-SCBD-114710-2 Organism Yellow fever virus (YFV 17D)Viruses
Yellow fever virus strain 17D (vaccine strain)
EN
EN
Nonstructural protein 1 (NS1) plays an essential role in immune evasion, pathogenesis, and viral replication. NS1 is required for the formation of the replication complex and recruitment of other nonstructural proteins to the endoplasmic reticulum. NS1 also travels to the plasma membrane, where it is excrete as a lipoparticle and binds to macrophages and dendritic cells. NS1 inhibits Toll-like receptor 3 signal transduction.
EN
EN
- UniProtKB - YFV polyprotein [ English ]
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