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Gene and DNA Sequence
Record information and status
Record ID
114725
Status
Published
Date of creation
2019-05-21 18:47 UTC (austein.mcloughlin@cbd.int)
Date of publication
2019-05-21 18:47 UTC (austein.mcloughlin@cbd.int)

General information
Name of the gene or DNA sequence
Nonstructural protein 5
Abbreviation
NS5
Category of DNA sequence
  • Protein coding sequence
Is the gene / DNA sequence is a synthetic molecule?
No
Donor organism
Donor organism
Yellow fever virus - YFV 17D
Donor organism point of collection
Yellow fever virus strain 17D (vaccine strain)
Characteristics of the protein coding sequence
Biological function
Nonstructural protein 5 (NS5) encodes a RNA-dependent RNA polymerase required for viral genome replication and capping of the 5' end of the viral genome. Additionally, NS5 also inhibits the interferon alpha/beta signalling pathway via the binding and inactivation of interferon-activated STAT2.
Additional Information
Other relevant website address or attached documents

Records referencing this document (3)
IDDescription
3record(s) found
Country's Decision or any other Communication1 record
Modified Organism1 record
Risk Assessment1 record