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Risk Assessment
Record information and status
Record ID
114757
Status
Published
Date of creation
2019-05-30 03:42 UTC (estaciojulietafe@gmail.com)
Date of publication
2019-05-30 03:42 UTC (estaciojulietafe@gmail.com)

General Information
Country
  • Philippines
Title of risk assessment
CONSOLIDATED REPORT OF SYNGENTA'S CORN MZHG0JG APPLICATION FOR DIRECT USE AS FOOD AND FEED, OR FOR PROCESSING
Date of the risk assessment
2018-08-29
Institution responsible for the risk assessment
Department of Agriculture
Elliptical Road, Diliman
Quezon City
Philippines, 1100
Phone:+632 920-3986,+632 924-1278 local 2802
Fax:+632 920-3986
Email:osec.da@gmail.com
Url:DA
Department of Environment and Natural Resources
Visayas Avenue
Quezon City
Philippines, 1100
Phone:+632 925-2329, +632 920-4352
Fax:+632 920-4301
Email:osec@denr.gov.ph
Url:DENR,PAWB
Department of Health
San Lazaro Compound, Sta. Cruz
Manila
Philippines
Phone:+632 651 7801; +623 651 7800
Fax:+632 743 1829
Email:etona@co.doh.gov.ph
Url:DOH Website
Contact details of the main responsible risk assessor
Ms. Ma. Lorelei U. Agbagala
Supervising Agriculturist
Post Entry Quarantine
Bureau of Plant Industry (BPI)
Economic Garden
Los Banos, Laguna
Philippines, 4030
Phone:+63 49 536 1678
Fax:+63 49 536 1678
Email:lorelieu5@gmail.com
Url:Bureau of Plant Industry
Risk assessment details
Living modified organism
SYN-ØØØJG-2 - Herbicide tolerant maize
Resistance to herbicides - Glufosinate, Glyphosate
Scope of the risk assessment
  • LMOs for direct use as feed
  • LMOs for direct use as food
  • LMOs for processing
Methodology and points to consider
Potential adverse effects identified in the risk assessment
The corn event has been approved as food and feed in US and Canada, and as food in New Zealand. The assessors agreed with the report that the transgenic plant is not a source of allergens. This was further confirmed by the results of gastric fluid digestibility studies, SDS-PAGE analysis and Western blot analysis. Consumption of corn as food may not drastically change due to the availability of transgenic corn varieties like MZHG0JG corn. Assessment from these countries proved the transgenic corn is not materially different in composition, safety, and other relevant parameters from corn-derived food and feed found in the market.
Likelihood that the potential adverse effects will be realized
The assessors have reported that mEPSPS and PAT are expressed independently of each other to retain their functional properties. The mEPSPS and PAT are integrated within the corn nuclear genome. Expression of the proteins were validated and confirmed by a series of tests that applied Southern blot, nucleotide sequencing of the nuclear genome and examination of inheritance pattern of the transgene over 3 generations of the transgenic MZHG0JG corn. The assessors confirmed that the expressed proteins do not interact with each other. They act as independent system conferring tolerance to herbicides of glufosinate or glyphosate composition.
Possible consequences:
The assessors found scientific evidence that the regulated article applied for human food and animal feed is as safe as its conventional counterpart and shall not pose any significant risk to human and animal
health.
Estimation of the overall risk
After a thorough scientific review and evaluation of the documents, the assessors find sufficient evidence
that the MZHG0JG corn applied for direct use will not pose any significant risk to health and
environment.
Recommendation(s)
The Department of Environment and Natural Resources - Biosafety Committee (DENR-BC), after a thorough scientific review and evaluation of the documents related to Environmental Risk along with the submitted
worn statement and accountability of the proponent, recommended the issuance of a biosafety permit for this regulated event provided that the conditions set by them are complied.

Also, the Department of Health - Biosafety Committee (DOH-BC), after a thorough scientific review and evaluation of documents related to Environmental Health Impact, concluded that corn MZHG0JG will not pose any significant risk to health and environment and that any hazards could be managed by the measures set by the department. DOH-BC also recommended for the issuance of biosafety permit for corn MZHG0JG.

Furthermore, the Socio-economic, Ethical and Cultural (SEC) Considerations expert also recommended for the issuance of biosafety permit for this regulated article after assessing the socio-economic, social and ethical indicators for the adoption of Genetically Modified Organisms.
Need(s) for further information on specific issues of concern
Corn MZHG0JG is found substantially equivalent to conventional counterpart and does not pose any significant risk to animal and human health.
Receiving environment(s) considered
This application is not for propagation of the Corn MZHG0JG. This LMO will be directly used for food, feed and for processing.
LMO detection and identification methods proposed
Quantitative diagnostic lateral flow strips, ELISA and PCR for routine quantitative and semi-quantitative detection of transgenes.  For higher sensitivity, real-time PCR may be used.
Additional Information
Additional Information
Corn MZHG0JG is intended for direct use as food, feed and for processing.

All relevant references submitted by the technology developer in their application; other references requested by the Scientific and Technical Review Panel (STRP) members, BAI, PPSSD, DENR, DOH and SEC Expert during the evaluation of this event.
Other relevant website address or attached documents