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Gene and DNA Sequence
Record information and status
Record ID
115269
Status
Published
Date of creation
2019-11-08 17:12 UTC (austein.mcloughlin@cbd.int)
Date of last update
2019-11-08 17:14 UTC (austein.mcloughlin@cbd.int)
Date of publication
2019-11-08 17:14 UTC (austein.mcloughlin@cbd.int)

General information
Name of the gene or DNA sequence
delta-6 elongase
Alternate Genetic Element Name (synonyms)
polyunsaturated fatty acid specific elongation enzyme 1
Δ6‐elongase
C18 Δ6-polyunsaturated fatty acid elongase
Abbreviation
D6E (PSE1)
Category of DNA sequence
  • Protein coding sequence
Is the gene / DNA sequence is a synthetic molecule?
No
Donor organism
Donor organism
Physcomitrella patens - spreading earthmoss, physcomitrella moss
Characteristics of the protein coding sequence
Biological function
Delta-6 elongase is involved in the biosynthesis of polyunsaturated fatty acids and catalyzes the addition of two carbon-hydrogen groups to the carboxyl end of γ-linolenic acid, converting it to dihomo-γ-linolenic acid.

Reactions:
malonyl-CoA + γ-linolenoyl-CoA + H+ → 3-oxodihomo γ-linolenoyl-CoA + CO2 + coenzyme A

malonyl-CoA + stearidonoyl-CoA + H+ → (8Z,11Z,14Z,17Z)-3-oxoicosatetraenoyl-CoA + CO2 + coenzyme A
Related trait(s) or use(s) in biotechnology
Additional Information
Additional Information
The sequence encodes a protein of 290 amino acids with an approximate weight of 34 kDa.