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Gene and DNA Sequence
Record information and status
Record ID
115573
Status
Published
Date of creation
2020-05-06 19:13 UTC (austein.mcloughlin@cbd.int)
Date of publication
2020-05-06 19:13 UTC (austein.mcloughlin@cbd.int)

General information
Name of the gene or DNA sequence
Neuraminidase
Abbreviation
NA
Category of DNA sequence
  • Protein coding sequence
Is the gene / DNA sequence is a synthetic molecule?
No
Donor organism
Donor organism
Influenza A virus - Influenza, Flu, Avian flu, Human flu, Swine influenza, Equine influenza, Bird flu
Characteristics of the protein coding sequence
Biological function
Neuraminidase (NA) catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates. The enzyme facilitates viral release during viral budding by cleaving terminal sialic acids on glycosylated hemagglutinin and prevent self-aggregation. NA may additionally facilitate the cell-to-cell spread of the virus by removing sialic acid residues from cell surfaces. Cleavage of sialic acid residues may also facilitate viral movement through mucus. NA plays a role in determining host range, replication and virulence.
Additional Information
Additional Information
Neuraminidase is denoted by an N number in the Influenza strain. There are 11 subtypes of NA in influenza A viruses.

Records referencing this document (1)
IDDescription
1record(s) found
Modified Organism1 record