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Gene and DNA Sequence
Record information and status
Record ID
115575
Status
Published
Date of creation
2020-05-06 20:18 UTC (austein.mcloughlin@cbd.int)
Date of last update
2020-05-06 20:19 UTC (austein.mcloughlin@cbd.int)
Date of publication
2020-05-06 20:19 UTC (austein.mcloughlin@cbd.int)

General information
Name of the gene or DNA sequence
Nuclear export protein
Alternate Genetic Element Name (synonyms)
Nonstructural protein 2
NS2
Abbreviation
NEP
Category of DNA sequence
  • Protein coding sequence
Is the gene / DNA sequence is a synthetic molecule?
No
Donor organism
Donor organism
Influenza A virus - Influenza, Flu, Avian flu, Human flu, Swine influenza, Equine influenza, Bird flu
Characteristics of the protein coding sequence
Biological function
Nuclear export protein (NEP) mediates the nuclear export of viral genomic RNAs, acting as an adaptor between the ribonucleoproteins (RNP; genomic RNA and nucleoprotein) and the host export machinery. The C-terminus of the protein binds to matrix protein 1 (M1), stabilizing the M1-RNP interaction. NEP may stimulate viral cRNA synthesis through the action of viral small RNAs and may recruit host F1F0 ATPase during budding.

Records referencing this document (1)
IDDescription
1record(s) found
Modified Organism1 record