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Gene and DNA Sequence
Record information and status
Record ID
115581
Status
Published
Date of creation
2020-05-08 19:21 UTC (austein.mcloughlin@cbd.int)
Date of last update
2020-05-08 19:33 UTC (austein.mcloughlin@cbd.int)
Date of publication
2020-05-08 19:33 UTC (austein.mcloughlin@cbd.int)

General information
Name of the gene or DNA sequence
Human polymerase 1 promoter
Alternate Genetic Element Name (synonyms)
rDNA promoter
rRNA promoter
Abbreviation
P-polI
Category of DNA sequence
  • Promoter
Is the gene / DNA sequence is a synthetic molecule?
No
Donor organism
Donor organism
Homo sapiens - HUMAN
Additional Information
Additional Information
The human polymerase I promoter contains the necessary sequences to recruit human RNA polymerase I (transcribes rRNA genes) and initiate transcription, rather than RNA polymerase II (transcribes protein coding genes) or RNA polymerase III (generally transcribes tRNA genes). In human cells, RNA Pol I only recognizes one promoter to synthesize 45S pre-rRNA, which will be processed into 5.8S, 18S and 28S rRNA. RNA Pol I synthesizes a triphosphate group at the 5' end of  the transcripts.

Records referencing this document (1)
IDDescription
1record(s) found
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