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Gene and DNA Sequence
Record information and status
Record ID
14995
Status
Published
Date of creation
2006-06-12 10:28 UTC (kirsty.mclean.consultant@cbd.int)
Date of last update
2014-02-27 15:02 UTC (dina.abdelhakim@cbd.int)
Date of publication
2014-02-27 15:02 UTC (dina.abdelhakim@cbd.int)

General information
Name of the gene or DNA sequence
Cry35Ab1
Abbreviation
CS-Cry35Ab1-BACTU
Category of DNA sequence
  • Protein coding sequence
Is the gene / DNA sequence is a synthetic molecule?
No
Donor organism
Donor organism
Bacillus thuringiensis - Bt, Bacillus, BACTU
Donor organism point of collection
Bacillus thuringiensis strain PS149B1
Characteristics of the protein coding sequence
Name of the protein expressed by the coding sequence
Cry35Ab1 delta-endotoxin
Biological function
The cry35Ab1 gene codes for a 44kDa Bt-toxin Cry35Ab1. When expressed with Cry34Ab1 it results in the mortality of Coleopteran insects, such as western corn rootworm (Diabrotica virgifera), northern corn rootworm (D. barberi), and mexican corn rootworm (D. virgifera zeae)  upon oral ingestion.
Related trait(s) or use(s) in biotechnology
Additional Information
Additional Information
Cry proteins, of which Cry34Ab1 is one among many, act by selectively binding to specific sites localized on the lining of the midgut of susceptible insect species. Following binding, pores are formed that disrupt midgut ion flow, causing gut paralysis and eventual death due to bacterial sepsis. Cry34Ab1 is lethal when eaten by the larvae of certain coleopteran insects (i.e., corn rootworms), and its specificity of action is directly attributable to the presence of specific binding sites in the target insects.

Records referencing this document (266)
IDDescription
266record(s) found
Country's Decision or any other Communication105 records
Information Resource1 record
Modified Organism49 records
Risk Assessment111 records