The stacked cotton line ACS-GHØØ1-3 x MON-15985-7 expresses three
novel proteins: the enzyme phosphinothricin acetyl-transferase
(PAT) and the delta-endotoxins Cry1Ac and Cry2Ab, both of which
confer resistance to the lepidopteran pests of cotton, such as the
cotton bollworm, pink bollworm and tobacco budworm.
The insecticidal proteins Cry1Ac and Cry2Ab are produced by the
cry1Ac and cry2Ab genes respectively, both of which were originally
isolated from the soil bacterium Bacillus thuringiensis and are
derived from MON-15985-7. The bar gene, which codes for the
production of PAT, is derived from ACS-GHØØ1-3. This enzyme renders
glufosinate ammonium inactive in the plant. The expression of the
bar gene allows the plant to survive the otherwise lethal
application of glufosinate ammonium. The bar gene was isolated from
Streptomyces hygroscopius, a gram-positive soil bacterium. The
novel traits of each parental line have been combined, through
traditional plant breeding, to produce this new cotton line.
For a full description of each parental line please refer to the
individual descriptions for the parent organisms.
This plant is a product of traditional plant breeding, and
therefore is not automatically subject to regulation in all
jurisdictions as are transgenic plants resulting from recombinant
DNA technologies. Certain jurisdictions may request notification in
advance of the release of a stacked hybrid, or may request
information to conduct an environmental and food safety assessment.
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