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Gene and DNA Sequence
Record information and status
Record ID
45860
Status
Published
Date of creation
2008-07-17 14:21 UTC (mia.crager@cbd.int)
Date of last update
2012-06-18 20:07 UTC (dina.abdelhakim@cbd.int)

General information
Name of the gene or DNA sequence
Erythromycin Ribosomal Methylase A
Abbreviation
CS-erm(A)
Category of DNA sequence
  • Protein coding sequence
Is the gene / DNA sequence is a synthetic molecule?
No
Donor organism
Donor organism
Streptococcus pneumoniae
Characteristics of the protein coding sequence
Name of the protein expressed by the coding sequence
Erythromycin Ribosomal Methylase A
Biological function
Confers resistance to the antibiotics erythromycin, azithromycin, clarithromycin, tetracycline, and roxithromycin, via methylation of a highly conserved adenine residue in the 23s rRNA leading to a conformational change in teh ribosome that prevents binding of erythromycin other macrolides, lincosamides and type B streptogramins.
Related trait(s) or use(s) in biotechnology
  • Resistance to antibiotics
Additional Information
Other relevant website address or attached documents

Records referencing this document (1)
IDDescription
1record(s) found
Modified Organism1 record

   
   
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