| | english | español | français |
Go to record ID

  Home|Finding Information|Record details   Printer-friendly version

Gene and DNA Sequence
Record information and status
Record ID
45875
Status
Published
Date of creation
2008-07-18 10:45 UTC (mia.crager@cbd.int)
Date of last update
2014-02-24 19:40 UTC (dina.abdelhakim@cbd.int)
Date of publication
2014-02-24 19:40 UTC (dina.abdelhakim@cbd.int)

General information
Name of the gene or DNA sequence
Beta-galactosidase gene
Abbreviation
CS-betagal-ECOLI
Category of DNA sequence
  • Protein coding sequence
Is the gene / DNA sequence is a synthetic molecule?
No
Donor organism
Donor organism
Escherichia coli - ECOLX
Characteristics of the protein coding sequence
Name of the protein expressed by the coding sequence
ß-Galactosidase
Biological function
β-galactosidase is a hydrolase enzyme that catalyzes the hydrolysis of β-galactosides into monosaccharides. Substrates of different β-galactosidases include ganglioside GM1, lactosylceramides, lactose, and various glycoproteins.

It is commonly used in molecular biology as a reporter marker to monitor gene expression. It also exhibits a phenomenon called α-complementation which forms the basis for the blue/white screening of recombinant clones. This enzyme can be split in two peptides, LacZα and LacZΩ, neither of which is active by itself but when both are present together, spontaneously reassemble into a functional enzyme.
Related trait(s) or use(s) in biotechnology
  • Selectable marker genes and reporter genes

Records referencing this document (31)
IDDescription
31record(s) found
Country's Decision or any other Communication16 records
Modified Organism6 records
Risk Assessment9 records