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Gene and DNA Sequence
Record information and status
Record ID
Date of creation
2010-11-04 19:55 UTC (manoela.miranda@cbd.int)
Date of last update
2021-06-22 18:04 UTC (austein.mcloughlin@cbd.int)
Date of publication
2021-06-22 18:04 UTC (austein.mcloughlin@cbd.int)

General information
Name of the gene or DNA sequence
Ti plasmid left border repeat
Category of DNA sequence
  • Plasmid vector
Is the gene / DNA sequence is a synthetic molecule?
Donor organism
Donor organism
Agrobacterium tumefaciens - Agrobacterium
Additional Information
Additional Information
The left border (LB) and right border (RB) of the Ti plasmid (tumour-inducing plasmid) are the signals that flank the T-DNA (transferred DNA) which is introduced into the plant genome upon being infected by the soil bacterium Agrobacterium tumefaciens.

When used in modern biotechnology for the development of LMOs, the virulent genes naturally occurring in Agrobacterium tumefaciens between the LB and RB are replaced by a DNA cassette containing the gene(s) of interest. Therefore, when a plant is transformed using Agrobacterium tumefaciens, the T-DNA containing the cassette with gene(s) of interest is integrated into the plant's genome.
Other relevant website address or attached documents

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