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Gene and DNA Sequence
Record information and status
Record ID
Date of creation
2011-01-20 10:55 UTC (german_bch@bvl.bund.de)
Date of last update
2012-07-26 14:39 UTC (dina.abdelhakim@cbd.int)
Date of publication
2012-07-26 14:39 UTC (dina.abdelhakim@cbd.int)

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General information
Name of the gene or DNA sequence
Stilbene Synthase
Category of DNA sequence
  • Protein coding sequence
Is the gene / DNA sequence is a synthetic molecule?
Donor organism
Donor organism
Vitis vinifera - Grape Vine
Characteristics of the protein coding sequence
Name of the protein expressed by the coding sequence
Stilbene Synthase
Biological function
Stilbene synthase catalyses the conversion of p-Cumaroyl-CoA to resveratrol.

Resveratrol (3,5,4-trihydroxy-trans-stilbene) belongs to the flavonoid group of compounds and is classed among the phytoalexins.Phytoalexins are a class of antibiotic polyphenol compounds that form part of the plant defence system.  Resveratrol was first identified and isolated from Japanese knotweed plants, but it is also present in grapevine (Vitis vinifera), pine, linseed, sesame seed and peanuts. In grapevine the highest concentration of resveratrol (between 50 and 100 μg/g) is found in the grape skins.

Resveratrol is a metabolite produced by the plant in response to stress, for instance, when subjected to high levels of ozone or ultra violet irradiation, or when under attack by fungi or insects. Beneficial effects on the human immune system have also been attributed to resveratrol. This is based mainly on its antioxidant properties. Resveratrol is primarily a scavenger of peroxy radicals. It reduces lipoprotein lipid (LDL) peroxidation and protects cell membranes against the damaging effects of oxidated LDL. Resveratrol is also thought to have anticarcinogenic and cancer-inhibiting properties.
Related trait(s) or use(s) in biotechnology
  • Tolerance to abiotic stress

Records referencing this document (4)
4record(s) found
Country's Decision or any other Communication1 record
Modified Organism2 records
Risk Assessment1 record