Due to the increasing cultivation of genetically modified plants and the use of genetic engineering in the production of food, the need for suitable detection methods for example for maize, rice, soya, tofu or bakery products increases. Sampling, residue analysis and the measures of the control agencies are regulated in a uniform manner throughout the EU.

The release of genetically modified organisms (GMO) for scientific trials needs to be approved by the BVL. If GMO are to be cultivated commercially, the BVL will provide a statement in the Community approval process of the EU. Furthermore, the BVL manages the international information exchange on GMO in the Biosafety Clearing House for Germany. The BVL hosts the secretary of the Central Committee on Biological Safety (ZKBS). The ZKBS advises the Federal Government and the Federal States in safety-relevant questions on genetic engineering.