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Genetic element (GENE)
published: 13 Nov 2018 last updated: 07 Feb 2019
Protein coding sequence
The mutagenised Cry51Aa2 variant protein, originally derived from soil bacterium Bacillus thuringuensis EG2934, is a member of the crystal (Cry) family of proteins that confer enhanced insecticidal activity against hemipteran and thysanopteran pests. Cry proteins, such as MCry51Aa2m, act by selectively binding to specific sites in the insect midgut and form pores, which disrupt the flow of ions, allowing water to enter the cells, cause destruction of the midgut lining by cellular lysis, and eventual death.