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Gene and DNA Sequence
Record information and status
Record ID
Date of creation
2019-05-21 18:42 UTC (austein.mcloughlin@cbd.int)
Date of publication
2019-05-21 18:42 UTC (austein.mcloughlin@cbd.int)

General information
Name of the gene or DNA sequence
Nonstructural protein 4B
Category of DNA sequence
  • Protein coding sequence
Is the gene / DNA sequence is a synthetic molecule?
Donor organism
Donor organism
Yellow fever virus - YFV 17D
Donor organism point of collection
Yellow fever virus strain 17D (vaccine strain)
Characteristics of the protein coding sequence
Biological function
Nonstructural protein 4B (NS4B) contributes to the formation of endoplasmic reticulum-derived vesicles during viral replication. Along with peptide 2K, NS4 also prevents the interferon-induced host phosphorylation of STAT1 and nuclear translocation, thereby preventing an interferon-triggered host antiviral state.
Additional Information
Other relevant website address or attached documents

Records referencing this document (3)
3record(s) found
Country's Decision or any other Communication1 record
Modified Organism1 record
Risk Assessment1 record