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Gene and DNA Sequence
Record information and status
Record ID
114725
Status
Published
Date of creation
2019-05-21 18:47 UTC (austein.mcloughlin@cbd.int)
Date of publication
2019-05-21 18:47 UTC (austein.mcloughlin@cbd.int)

General information
Name of the gene or DNA sequence
Nonstructural protein 5
Abbreviation
NS5
Category of DNA sequence
  • Protein coding sequence
Is the gene / DNA sequence is a synthetic molecule?
No
Donor organism
Donor organism
Yellow fever virus - YFV 17D
Donor organism point of collection
Yellow fever virus strain 17D (vaccine strain)
Characteristics of the protein coding sequence
Biological function
Nonstructural protein 5 (NS5) encodes a RNA-dependent RNA polymerase required for viral genome replication and capping of the 5' end of the viral genome. Additionally, NS5 also inhibits the interferon alpha/beta signalling pathway via the binding and inactivation of interferon-activated STAT2.
Additional Information
Other relevant website address or attached documents

Records referencing this document (1)
IDDescription
1record(s) found
Modified Organism1 record