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Gene and DNA Sequence
Record information and status
Record ID
Date of creation
2019-12-09 07:32 UTC (anita@kats.gov.my)
Date of publication
2020-01-06 17:38 UTC (austein.mcloughlin@cbd.int)

General information
Name of the gene or DNA sequence
Acyl-homoserine lactonase SP24
Alternate Genetic Element Name (synonyms)
Category of DNA sequence
  • Protein coding sequence
Is the gene / DNA sequence is a synthetic molecule?
Donor organism
Donor organism
Bacillus thuringiensis - Bt, Bacillus, BACTU
Donor organism point of collection
AHL-lactonase SP24 isolated from Bacillus thuringiensis obtained from rice rhizosphere soil.
Characteristics of the protein coding sequence
Name of the protein expressed by the coding sequence
Lactonase Enzyme
Biological function
The enzyme hydrolyzes N-acyl-homoserine lactones (AHLs) molecules secreted by Gram-negative bacteria, such as Erwinia mallotivora. AHLs have been determined to be the principle signalling molecule involved in quorum sensing (cell-to-cell communication) in Gram-negative bacteria and are essential for survival and regulation of virulence genes. Bacteria lacking AHLs are non-pathogenic.
Related trait(s) or use(s) in biotechnology
  • Resistance to Gram-negative bacteria
Additional Information
Additional Information
Plants modified for quorum quenching (degradation of quorum sensing signalling molecules) have been shown to convey increased protection to bacterial infection.

Records referencing this document (3)
3record(s) found
Country's Decision or any other Communication1 record
Modified Organism1 record
Risk Assessment1 record