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Genetic element
(GENE)
last updated: 08 May 2020
Human polymerase 1 promoter
EN
-
rDNA promoterEN
-
rRNA promoterEN
P-polI
EN
Promoter
No
-
BCH-ORGA-SCBD-45743-4 Organism Homo sapiens (HUMAN)Mammals
EN
The human polymerase I promoter contains the necessary sequences to recruit human RNA polymerase I (transcribes rRNA genes) and initiate transcription, rather than RNA polymerase II (transcribes protein coding genes) or RNA polymerase III (generally transcribes tRNA genes). In human cells, RNA Pol I only recognizes one promoter to synthesize 45S pre-rRNA, which will be processed into 5.8S, 18S and 28S rRNA. RNA Pol I synthesizes a triphosphate group at the 5' end of the transcripts.
EN
- RNA polymerase I catalysed transcription of insert viral cDNA.pdf [ English ]
- Basic Mechanisms in RNA Polymerase I Transcription of the Ribosomal RNA Genes.pdf [ English ]
- Human RNA Polymerase I-Driven Reverse Genetics for Influenza A Virus in Canine Cell.pdf [ English ]
- Structure of the initiation-competent RNA polymerase I and its implication for transcription.pdf [ English ]
- Unidirectional RNA polymerase I–polymerase II transcription system for the generation of influenza A virus from eight plasmids.pdf [ English ]
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