Phytase | Escherichia coli (ECOLX) | BCH-GENE-SCBD-115828 | Genetic element | Biosafety Clearing-House

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Genetic element (GENE)
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last updated: 04 Dec 2020
General information
Phytase
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  • Phosphoanhydride phosphorylase
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  • appA
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phy02
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Protein coding sequence
No
Donor organism
The phy02 sequence was derived from the E. coli strain K12 appA gene. Site-directed mutagenesis was applied to introduce amino acid changes for increased thermostability and gastric digestion resilience.
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Characteristics of the protein coding sequence
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Phytases catalyze the removal of phosphate groups from phytate (phytic acid). The enzyme promotes the hydrolysis of the phosphoester bond, producing inositol and phosphate.
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Additional Information
Phytases are often added to animal feed to improve digestibility as plants store phosphorous in an indigestible form, phytic acid, which is considered an antinutrient (chelating iron, zinc, magnesium and calcium) and its excretion can lead to environmental phosphate pollution.
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Records referencing this document Show in search
Record type Field Record(s)
Living Modified Organism Introduced or modified genetic element(s) 1
Living Modified Organism Genetic elements construct 1