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Gene and DNA Sequence
Record information and status
Record ID
Date of creation
2020-12-04 20:37 UTC (austein.mcloughlin@cbd.int)
Date of publication
2020-12-04 20:37 UTC (austein.mcloughlin@cbd.int)

General information
Name of the gene or DNA sequence
Alternate Genetic Element Name (synonyms)
Phosphoanhydride phosphorylase
Category of DNA sequence
  • Protein coding sequence
Is the gene / DNA sequence is a synthetic molecule?
Donor organism
Donor organism
Escherichia coli - ECOLX
Donor organism point of collection
The phy02 sequence was derived from the E. coli strain K12 appA gene. Site-directed mutagenesis was applied to introduce amino acid changes for increased thermostability and gastric digestion resilience.
Characteristics of the protein coding sequence
Biological function
Phytases catalyze the removal of phosphate groups from phytate (phytic acid). The enzyme promotes the hydrolysis of the phosphoester bond, producing inositol and phosphate.
Related trait(s) or use(s) in biotechnology
  • Changes in quality and/or metabolite content
  • Improved digestibility/digestion
  • Increased phosphorous bioavailability
Additional Information
Additional Information
Phytases are often added to animal feed to improve digestibility as plants store phosphorous in an indigestible form, phytic acid, which is considered an antinutrient (chelating iron, zinc, magnesium and calcium) and its excretion can lead to environmental phosphate pollution.

Records referencing this document (1)
1record(s) found
Modified Organism1 record