GMO Genetic Elements Thesaurus (GMO‑GET): a controlled vocabulary for the consensus designation of introduced or modified genetic elements in genetically modified organisms (Feb 2021) | BCH-VLR-SCBD-115889 | Biosafety Virtual Library Resources | Biosafety Clearing-House

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last updated: 16 Feb 2021

General Information
GMO Genetic Elements Thesaurus (GMO‑GET): a controlled vocabulary for the consensus designation of introduced or modified genetic elements in genetically modified organisms
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Paulien Adamse, Emilie Dagand, Karen Bohmert-Tatarev, Daniela Wahler, Manoela Miranda, Esther J. Kok, Joachim Bendiek Corresponding author: Paulien Adamse
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Federal Office of Consumer Protection and Food Safety (BVL)   BCH-ORG-SCBD-102445-2
  • Government agency (National/Federal)
Wageningen Food Safety Research (WFSR), Wageningen University & Research (Formely RIKILT Wageningen University & Research) (WFSR)   BCH-ORG-SCBD-102567-9
  • Other (Non-profit research organisation)
Wageningen Food Safety Research (WFSR), Wageningen University & Research PO Box 230
Wageningen, Gelderland
6700 AE, Netherlands
Phone: +31 317 480256,
Fax: +31 317 417717,
BMC Bioinformatics Springer Nature For locations: https://group.springernature.com/gp/group/about-us/locations-contact
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2021-02
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Peer-reviewed journal article
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Open access
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Information on the content of the resource
Background
Various databases on genetically modified organisms (GMOs) exist, all with their specific focus to facilitate access to information needed for, e. g., the assistance in risk assessment, the development of detection and identification strategies or inspection and control activities. Each database has its unique approach towards the subject. Often these databases use different terminology to describe the GMOs. For adequate GMO addressing and identification and exchange of GMO-related information it is necessary to use commonly agreed upon concepts and terminology.

Result
A hierarchically structured controlled vocabulary describing the genetic elements inserted into conventional GMOs, and GMOs developed by the use of gen(om)e-editing is presented: the GMO genetic element thesaurus (GMO-GET). GMO-GET can be used for GMO-related documentation, including GMO-related databases. It has initially been developed on the basis of two GMO databases, i.e. the Biosafety Clearing-House and the EUginius database.

Conclusion
The use of GMO-GET will enable consistent and compatible information (harmonisation), also allowing an accurate exchange of information between the different data systems and thereby facilitating their interoperability. GMO-GET can also be used to describe genetic elements that are altered in organisms obtained through current targeted genome-editing techniques.
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Keywords for facilitating searching for information in the clearing-houses

https://bch.cbd.int/onlineconferences/ra_guidance_references.shtml

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Additional Information
Identifier (ISBN, ISSN, etc.)
DOI: 10.1186/s12859-020-03880-0
Format
PDF - 1.42 MB (15 pages)
Keywords and any other relevant information
Thesaurus; Vocabulary; Genetic elements; LMO; GMO; Database; Detection; Information exchange
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