Beta-lactamase gene | BCH-GENE-SCBD-14975 | Genetic element | Biosafety Clearing-House

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Genetic element (GENE)

published: 09 Jun 2006 last updated: 26 Feb 2014
General information
Beta-lactamase gene
EN
CS-bla-ECOLX
EN
Protein coding sequence
No
Donor organism
EN
Characteristics of the protein coding sequence
beta-lactamase
EN
Beta-lactamases are enzymes produced by some bacteria and are responsible for their resistance to beta-lactam antibiotics like penicillins, cephamycins, and carbapenems (ertapenem) (Cephalosporins are relatively resistant to beta-lactamase).

These antibiotics have a common element in their molecular structure: a four-atom ring known as a beta-lactam. The lactamase enzyme breaks that ring open, deactivating the molecule's antibacterial properties
EN
Additional Information
EN
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Record type Field Record(s)
Laboratory for detection and identification of LMOs Genetic element(s) detectable by the laboratory 1
Living Modified Organism Introduced or modified genetic element(s) 26
Living Modified Organism Genetic elements construct 9