Cry3Bb1 | BCH-GENE-SCBD-14993 | Genetic element | Biosafety Clearing-House

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Genetic element (GENE)

published: 12 Jun 2006 last updated: 27 Feb 2014
General information
Cry3Bb1
EN
  • CryIIIB2
    EN
CS-Cry3Bb1-BACTU
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Protein coding sequence
No
Donor organism
Bacillus thuringiensis subsp. kumamotoensis; strain EG4691
EN
Characteristics of the protein coding sequence
Cry3Bb1 delta-endotoxin
EN
The cry3Bb1 gene, isolated from the soil bacterium Bacillus thuringiensis (Bt) subspecies kumamotoensis, produces the insect control protein Cry3Bb1, a delta-endotoxin. The Cry3Bb1 protein provides protection against the western corn rootworm (Diabrotica vigifera) and northern corn rootworm (Diabrotica barberi).
EN
Additional Information
Cry proteins, of which Cry3Bb1 is only one, act by selectively binding to specific sites localized on the lining of the midgut of susceptible insect species. Following binding, pores are formed that disrupt midgut ion flow, causing gut paralysis and eventual death due to bacterial sepsis. Cry3Bb1 is lethal only when eaten by the larvae of coleopteran insects (i.e., beetles), and its specificity of action is directly attributable to the presence of specific binding sites in the target insects.
EN
Records referencing this document Show in search
Record type Field Record(s)
Living Modified Organism Introduced or modified genetic element(s) 71
Living Modified Organism Genetic elements construct 70
Laboratory for detection and identification of LMOs Genetic element(s) detectable by the laboratory 2