REN-ØØØ38-3 × MON-ØØ81Ø-6 - Mavera™YieldGard™ maize | BCH-LMO-SCBD-15104 | Living Modified Organism | Biosafety Clearing-House


Living Modified Organism (LMO)

Decisions on the LMO Risk Assessments  
published: 19 Jun 2006 last updated: 12 Feb 2014
Living Modified Organism identity
The image below identifies the LMO through its unique identifier, trade name and a link to this page of the BCH. Click on it to download a larger image on your computer. For help on how to use it go to the LMO quick-links page.
Mavera™YieldGard™ maize
LY038 x MON810
REN-ØØØ38-3 × MON-ØØ81Ø-6
A stacked insect-resistant and increased-lysine maize derived from conventional cross-breeding of REN-ØØØ38-3 and MON-ØØ81Ø-6.  An increase in content of the amino acid lysine is produced through incorporation of the cordapA gene and resistance to lepidopteran insects from the cry1Ab gene from Bacillus thuringiensis subsp. kurstaki. The nptII gene insert was removed using the Cre/Lox system following genetic transformation and selection.
The term “Recipient organism” refers to an organism (either already modified or non-modified) that was subjected to genetic modification, whereas “Parental organisms” refers to those that were involved in cross breeding or cell fusion.
  • BCH-ORGA-SCBD-246-6 Organism Zea mays (Maize, Corn, MAIZE)
  • BCH-LMO-SCBD-15103-8 Living Modified Organism REN-ØØØ38-3 - Mavera™ maize
    Changes in quality and/or metabolite content (Protein and amino acids)
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    BCH-LMO-SCBD-14750-19 Living Modified Organism MON-ØØ81Ø-6 - YieldGard™ maize
    Monsanto | Resistance to diseases and pests (Insects, Lepidoptera (butterflies and moths), European corn borer (Ostrinia nubilalis))
Inbred corn lines (and/or isolines) developed and produced by Monsanto.
Characteristics of the modification process
  • Cross breeding
Some of these genetic elements may be present as fragments or truncated forms. Please see notes below, where applicable.
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    BCH-GENE-SCBD-14978-3 Dihydrodipicolinate synthase | Corynebacterium glutamicum (CORGT)
    Protein coding sequence | Changes in quality and/or metabolite content (Protein and amino acids)
  • BCH-GENE-SCBD-14985-12 Cry1Ab | Bacillus thuringiensis (Bt, Bacillus, BACTU)
    Protein coding sequence | Resistance to diseases and pests (Insects, Lepidoptera (butterflies and moths))
  • BCH-GENE-SCBD-100366-6 CaMV Enhanced 35S promoter | Cauliflower mosaic virus (CaMV)
  • BCH-GENE-SCBD-100359-7 Hsp70 intron | Zea mays (Maize, Corn, MAIZE)
  • BCH-GENE-SCBD-103623-3 Globulin 1 Promotor | Zea mays (Maize, Corn, MAIZE)
  • BCH-GENE-SCBD-100355-6 Rice actin 1, intron | Oryza sativa (Rice, ORYSA)
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    BCH-GENE-SCBD-104383-1 Dihydrodipicolinate synthase chloroplast targeting sequence | Zea mays (Maize, Corn, MAIZE)
    Transit signal
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    BCH-GENE-SCBD-103624-3 Globulin 1 Terminator | Zea mays (Maize, Corn, MAIZE)
DNA Insert from MON810, Vectors PV-ZMBK07 and PV-ZMGT10
MON810 contains one integrated DNA consisting of P-e35S, I-Hsp70 and cry1Ab. The terminator of the nopaline synthase (nos) gene was lost due to a truncation at the 3' end of the gene cassette during genome integration and is, therefore, not present in MON810.

DNA Insert from LY038, Vector PV-ZMPQ76
The linear DNA fragment used in the transformation included two expression cassettes, each with a single copy of a gene: cordapA, and  nptII. The 3′ nontranslated region of the globulin 1 gene contains the polyadenylation signal.The nptII gene cassette confers the paromomycin resistance that permits the selection of cells containing the expression cassette. The selectable marker gene nptII was used during the initial transformation and tissue culture process, and was removed using the Cre/Lox system following selection of the line.

For additional information on this LMO, please refer to the records of the parental LMOs.
LMO characteristics
  • Feed
Additional Information
LY038 x MON810 is a product of traditional plant breeding, and therefore is not automatically subject to regulation in all jurisdictions as are transgenic plants resulting from recombinant DNA technologies. Certain jurisdictions may request notification in advance of the release of a stacked hybrid, or may request information to conduct an environmental and food safety assessment.