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Gene and DNA Sequence
Record information and status
Record ID
Date of creation
2009-03-05 14:27 UTC (manoela.miranda@cbd.int)
Date of last update
2021-02-18 17:16 UTC (austein.mcloughlin@cbd.int)
Date of publication
2021-02-18 17:16 UTC (austein.mcloughlin@cbd.int)

General information
Name of the gene or DNA sequence
Glyphosate-N-Acteyltransferase gene
Category of DNA sequence
  • Protein coding sequence
Is the gene / DNA sequence is a synthetic molecule?
Donor organism
Donor organism
Bacillus licheniformis - BACLI
Characteristics of the protein coding sequence
Name of the protein expressed by the coding sequence
Biological function
Glyphosate-N-acetyltransferase expression in genetically modified plants may lead to detoxification of the glyphosate agent. This is brought about by the transfer of an acetyl group from acetyl CoA to the secondary amine group of glyphosate.

The resulting N-acetylglyphosate does not have the ability to inhibit the activity of the EPSPS enzyme, and the genetically modified plants are able to grow despite glyphosate treatment.
Related trait(s) or use(s) in biotechnology
Additional Information
Additional Information
Two modified versions of the GAT gene were developed using a DNA shuffling technique using the GAT coding sequences from 3 separate strains of B. licheniformis (Strains B6, 401 and DS3).
The two versions are known as GAT4621 and GAT4601.

Records referencing this document (82)
82record(s) found
Country's Decision or any other Communication33 records
Modified Organism9 records
Risk Assessment40 records