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Gene and DNA Sequence
Record information and status
Record ID
Date of creation
2009-03-05 14:35 UTC (manoela.miranda@cbd.int)
Date of last update
2021-02-15 14:42 UTC (austein.mcloughlin@cbd.int)
Date of publication
2021-02-15 14:42 UTC (austein.mcloughlin@cbd.int)

General information
Name of the gene or DNA sequence
Acetohydroxyacid synthase gene
Alternate Genetic Element Name (synonyms)
Acetolactate synthase gene (ALS)
Category of DNA sequence
  • Protein coding sequence
Is the gene / DNA sequence is a synthetic molecule?
Donor organism
Donor organism
Zea mays - Maize, Corn, MAIZE
Characteristics of the protein coding sequence
Name of the protein expressed by the coding sequence
Acetohydroxyacid synthase
Biological function
The acetolactate synthase enzyme (ALS) plays a key role in the biochemical pathways of the branched-chain amino acids leucine, isoleucine and valine. The application of ALS-inhibiting herbicides blocks this synthesis pathway. Lack of the aforementioned amino acids interferes with protein synthesis, causing the plant to die off.This gene encodes a modified acetolactate synthase, which confers tolerance to several acetolactate synthase-inhibiting herbicides such as, for example, sulfonylurea.
Related trait(s) or use(s) in biotechnology
Additional Information

Records referencing this document (24)
24record(s) found
Country's Decision or any other Communication8 records
Modified Organism4 records
Risk Assessment12 records