SYN-ØØØ98-3 - Insect resistant herbicide tolerant maize | BCH-LMO-SCBD-111968 | Living Modified Organism | Biosafety Clearing-House

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Living Modified Organism (LMO)

Decisions on the LMO Risk Assessments  
last updated: 01 Jun 2017
Living Modified Organism identity
The image below identifies the LMO through its unique identifier, trade name and a link to this page of the BCH. Click on it to download a larger image on your computer. For help on how to use it go to the LMO quick-links page.
Insect resistant herbicide tolerant maize
EN
MZIR098
Yes
SYN-ØØØ98-3
  • - Person: Syngenta (Novartis (Ciba-Geigy)) | BCH-CON-NZ-8060-1
    Person:
    Syngenta (Novartis (Ciba-Geigy))
    Phone:
    Fax:
    Email:
    Website:
MZIR098 plants were modified to contain genes expressing ecry3.1Ab, mcry3A, and phosphinothricin acetyltransferase. These modification are intended to protect against certain coleopteran pests including western corn rootworm. Expression of the PAT gene, confers tolerance to glufosinate-ammonium herbicides and is used as a selection marker.
EN
The term “Recipient organism” refers to an organism (either already modified or non-modified) that was subjected to genetic modification, whereas “Parental organisms” refers to those that were involved in cross breeding or cell fusion.
Corn line: NP2222
EN
Characteristics of the modification process
pSYN17629
EN
  • Agrobacterium-mediated DNA transfer
Some of these genetic elements may be present as fragments or truncated forms. Please see notes below, where applicable.
  • BCH-GENE-SCBD-100270-6 Nopaline Synthase Gene Promoter | Agrobacterium tumefaciens (Agrobacterium)
    Promoter
  • BCH-GENE-SCBD-104789-2 eCry3.1Ab | Bacillus thuringiensis (Bt, Bacillus, BACTU)
    Protein coding sequence | Resistance to diseases and pests (Insects, Coleoptera (beetles), Western corn rootworm (Diabrotica virgifera), Northern corn rootworm (Diabrotica barberi))
  • BCH-GENE-SCBD-100269-8 Nopaline Synthase Gene Terminator | Agrobacterium tumefaciens (Agrobacterium)
    Terminator
  • BCH-GENE-SCBD-100362-7 Ubiquitin gene promoter | Zea mays (Maize, Corn, MAIZE)
    Promoter
  • BCH-GENE-SCBD-43634-3 mCry3A | Bacillus thuringiensis (Bt, Bacillus, BACTU)
    Protein coding sequence | Resistance to diseases and pests (Insects, Coleoptera (beetles), Western corn rootworm (Diabrotica virgifera))
  • BCH-GENE-SCBD-100287-7 CaMV 35S promoter | Cauliflower mosaic virus (CaMV)
    Promoter
  • BCH-GENE-SCBD-15002-4 Phosphinothricin N-acetyltransferase gene | Streptomyces viridochromogenes (STRVR)
    Protein coding sequence | Resistance to herbicides (Glufosinate)
  • BCH-GENE-SCBD-111966-2 Nopaline Synthase Enhancer | Agrobacterium tumefaciens (Agrobacterium)
    Leader
  • BCH-GENE-SCBD-104788-2 Cestrum Yellow Leaf Curling Virus promoter | Cestrum yellow leaf curling virus (CYLCV)
    Promoter
Molecular characterization of MZIR098 was carried out using nucleotide sequencing and Southern blot analyses. These analyses indicated that a single copy of the T-DNA was inserted in to the genome of the recipient organism and that and it does not contain the plasmid backbone sequence from transformation plasmid pSYN17629. Sequence analysis of the MZIR098 insertion site demonstrated that 24-bp from the corn genomic sequence was deleted during the integration of the MZIR098 insert.
EN
LMO characteristics
EN
  • Food
Detection method(s)
EN
Additional Information
EN
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