DAS-Ø15Ø7-1 x MON-ØØ81Ø-6 x SYN-IR6Ø4-5 - Insect resistant herbicide tolerant maize | BCH-LMO-SCBD-112717 | Living Modified Organism | Biosafety Clearing-House

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Living Modified Organism (LMO)

Decisions on the LMO Risk Assessments  
last updated: 09 Feb 2021
Living Modified Organism identity
The image below identifies the LMO through its unique identifier, trade name and a link to this page of the BCH. Click on it to download a larger image on your computer. For help on how to use it go to the LMO quick-links page.
Insect resistant herbicide tolerant maize
EN
TC1507 x MON810 x MIR604
DAS-Ø15Ø7-1 x MON-ØØ81Ø-6 x SYN-IR6Ø4-5
  • - Organization: Dupont Poineer () | BCH-CON-SCBD-106199-2
    Organization
    Dupont Poineer ()
    Private sector (business and industry)
    Chestnut Run Plaza 720/1S5 974 Centre Road
    Wilmington,, Delaware
    19805, United States of America
    Phone:
    Fax:
    Email:
    Website:
The stacked maize line TC1507×MON810×MIR604 was obtained through the traditional cross breading of each of the parental organisms to produce a maize that expresses each of cry1F, pat, cry1Ab, and cry3Aa2 genes. The expression of these genes are expected to confer resistance to Lepidoptera and Coleoptera, and tolerant to glufosinate herbicide.
EN
The term “Recipient organism” refers to an organism (either already modified or non-modified) that was subjected to genetic modification, whereas “Parental organisms” refers to those that were involved in cross breeding or cell fusion.
  • BCH-ORGA-SCBD-246-6 Organism Zea mays (Maize, Corn, MAIZE)
    Crops
  • BCH-LMO-SCBD-14841-13 Living Modified Organism DAS-Ø15Ø7-1 - Herculex™ I maize
    Resistance to diseases and pests (Insects, Lepidoptera (butterflies and moths)), Resistance to herbicides (Glufosinate)
  • BCH-LMO-SCBD-14750-19 Living Modified Organism MON-ØØ81Ø-6 - YieldGard™ maize
    Resistance to diseases and pests - Insects - Lepidoptera (butterflies and moths)
  • BCH-LMO-SCBD-15105-12 Living Modified Organism SYN-IR6Ø4-5 - Agrisure™ RW Rootworm-Protected maize
    Mannose tolerance Resistance to diseases and pests - Insects - Coleoptera (beetles) - Western corn rootworm (Diabrotica virgifera) Selectable marker genes and reporter genes
EN
Characteristics of the modification process
PHI8999A, PV-ZMBK07, and pZM26
EN
  • Cross breeding
Some of these genetic elements may be present as fragments or truncated forms. Please see notes below, where applicable.
DNA insert from TC1507 vector PHI8999A
TC1507 modified with the insertion of the Cry1F gene to confer resistance to the European corn borer (Ostrinia nubilalis). A transformation cassette coding for phosphinothricin (PPT) herbicide tolerance, specifically glufosinate ammonium, was also inserted into the organism.

DNA insert from MON810 vector PV-ZMBK07
MON810 contains a truncated portion of a synthetic form of the cry1Ab gene which confers resistance against lepidoptera

DNA insert from MIR604 vector pZM26
Cry3A gene was modified for enhanced expression in maize and such that the amino acid sequence of the synthetic version of Cry3A is the same as the native protein, except for the modified serine-protease recognition site. The pmi gene encodes the enzyme phosphomannose isomerase (PMI) that allows the plants to utilise mannose as a carbon source and is used as a selectable marker.

For additional information on this LMO, please refer to the records of the parental LMOs.
EN
LMO characteristics
EN
  • Food
  • Feed
Additional Information
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