Influenza A virus (Influenza, Flu, Avian flu, Human flu, Swine influenza, Equine influenza, Bird flu) | BCH-ORGA-SCBD-45782 | Organism | Biosafety Clearing-House

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Organism (ORGA)

last updated: 01 May 2020
Organism information
Influenza A virus
Phylum Negarnaviricota
Class Insthoviricetes
Order Articulavirales
Family Orthomyxoviridae
Genus Alphainfluenzavirus
Species Influenza A virus
  • Influenza
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  • Flu
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  • Avian flu
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  • Human flu
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  • Swine influenza
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  • Equine influenza
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  • Bird flu
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Viruses
Characteristics related to biosafety
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Influenza viruses that cause influenza in vertebrates, including birds, humans, and other mammals.
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  • Vaccine
Additional Information
Influenza A virus genome is comprised of 8 negative-sense RNA segments, encoding 10 proteins (hemagglutinin (HA), neuraminidase (N), membrane channel protein, nucleoprotein, matrix protein, polymerase basic 1, polymerase basic 2, polymerase acidic protein, nonstructural protein 1 and nonstructural protein 2). The HA protein is categorized into 18 subtypes and confers the H number in the influenza strain (e.g. H1, H3, etc). Similarly, the N protein has 11 sub-types and confers the N number in the influenza strain (e.g. N1, N2, etc.). During co-infection of two strains, reassortment can occur to produce new strains of influenza.
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